SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses. The discovery may ...

The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing ...

All cellular life—from humans to bacteria—possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

Immunology has transformed humanity’s understanding of oneself and its battle against disease. Inflammation which is a primordial defense mechanism against pathogens, also acts as a double-edged sword ...

Researchers at the Francis Crick Institute, King's College London and Complutense University of Madrid have shown that γδ T ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

Researchers from Penn’s School of Dental Medicine discovered that training the innate immune system may lead to increased bone loss in inflammatory conditions such as periodontitis and arthritis.