Our ability to study networks within the nervous system has been limited by the tools available to observe large volumes of cells at once. An ultra-fast, 3D imaging technique called SCAPE microscopy, ...

High-speed SCAPE microscopy was used to capture the activity of proprioceptive neurons inside a freely moving fruit fly larvae. By creating 3D, live action images of nerve cells in larvae as the ...

This schematic depicts SCAPE's imaging geometry. The sample is illuminated by a thin sheet of light (blue), incident at an oblique angle. SCAPE achieves high speed imaging by sweeping this light sheet ...