Exploration means looking around, observing, describing and mapping undiscovered territory, not testing theories or models. The goal is to discover things we neither knew or expected, and to see ...

For more than three decades, researchers studying genomes have relied on foundational resources such as Repbase and, more ...

Most pockets in the human leukocyte antigen–group DR (HLA-DR) groove are shaped by clusters of polymorphic residues and, thus, have distinct chemical and size characteristics in different HLA-DR ...

Background Hepatocellular carcinoma (HCC), one of the most prevalent cancers worldwide, has a high mortality owing to diagnostic challenges and therapeutic resistance. Lactate metabolism and protein ...

Together, we provide the first integrated view of DNA methylation and global transcription in clinical isolates of P. falciparum, elucidating a multilayered regulatory mechanism of parasite adaptation ...

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