Given that extreme weather disturbances frequently threaten the safe and stable operation of new power systems, the uncertainty of source–load forecasting has become a particular bottleneck affecting ...
Tuberculosis (TB) today remains the leading cause of death by infectious diseases. Drug-resistant TB is a global public health problem and of greatest concern is resistance to the first-line drug ...
Mild cognitive impairment (MCI) is a nervous system disease, and its clinical status can be used as an early warning of Alzheimer's disease (AD). Subtle and slow changes in brain structure between ...
In reaction discovery, the search space of discrete reaction parameters such as catalyst structure is often not explored systematically. We have developed a tool set to aid the search of optimal ...
visualized (Dashboard): https://www.covid19.admin.ch/en/overview published as 'open government data': https://opendata.swiss/en/dataset/covid-19-schweiz The aim of ...
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1
ABCB1 is a membrane transport protein that protects cells from toxic compounds. At the same time, it limits the uptake of orally administered drugs and contributes to multidrug resistance in cancer ...
A small, 49-residue protein, AcrZ, has recently been identified in genetic screens as a binding partner of AcrB that affects substrate preference 8. A mutant strain of E. coli lacking AcrZ is ...
Being able to predict the course of arbitrary chemical reactions is essential to the theory and applications of organic chemistry. Approaches to the reaction prediction problems can be organized ...
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