University of California, San Francisco

Genetic Test Ranks Risk for Black People Hoping to Donate a Kidney

A UCSF study followed Black kidney donors to see if they faced elevated risks for low kidney function, and found that many ...
eLife

Deciphering interferon functions in avian influenza using receptor knockout models in the natural host

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.
Lupus Science & Medicine

Prognostic value of baseline clinical features in SLE: a cluster analysis

Objective SLE is a heterogeneous systemic autoimmune disease with diverse clinical manifestations. We aimed to identify ...
Times Higher Education

West Virginia University

Choosing West Virginia University (WVU) means choosing an education that will set you up for the future. Pioneering research, academic excellence and forward-thinking values combined with a unique ...
Times Higher Education

California State University, Los Angeles

Basic information and contact details for California State University, Los Angeles Established in 1947, the California State University, Los Angeles (Cal State LA) is located in the heart of Los ...
snmjournals.org

Striatal Dopamine Transporter Availability Associated with Polymorphisms in the Dopamine Transporter Gene SLC6A3

Polymorphisms in the gene SLC6A3 for the dopamine transporter (DAT) have been associated with DAT availability in the human brain. This finding suggests an effect of these polymorphisms, or of ...
BMJ

Differentiation between athlete’s heart and dilated cardiomyopathy in athletic individuals

Objective Distinguishing early dilated cardiomyopathy (DCM) from physiological left ventricular (LV) dilatation with LV ejection fraction <55% in athletes (grey zone) is challenging. We evaluated the ...
eLife

Parabrachial CGRP neurons modulate active defensive behavior under a naturalistic threat

Recent studies suggest that calcitonin gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) represent aversive information and signal a general alarm to the forebrain. If CGRP neurons ...
Frontiers

Identification of core genes in intervertebral disc degeneration using bioinformatics and machine learning algorithms

Gene expression profiles, including those from 35 LDH patients and 43 healthy volunteers, were downloaded from the GEO database (GSE124272, GSE150408, GSE23130, GSE153761). After merging four ...
ascopubs.org

Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer

RNA-Based Homologous Recombination Deficiency Signature Detects Homologous Recombination Deficiency-RNA+ Patients With and Without Homologous Recombination Repair Gene Pathogenic Alterations in Men ...
Europe PMC

Identification and analysis of key genes in adipose tissue for human obesity based on bioinformatics.

Obesity is a complex condition that is affected by a variety of factors, including the environment, behavior, and genetics. However, the genetic mechanisms underlying obesity remains poorly elucidated ...
BMJ

Randomised double-blind controlled trial of non-invasive preimplantation genetic testing for aneuploidy in in vitro fertilisation: a protocol paper

Introduction The success rate of in vitro fertilisation (IVF) treatment for couples with infertility remains low due to lack of a reliable tool in selecting euploid embryos for transfer. This study ...