New Autism Treatment Strategy Restores Key Brain Receptor Function

An antisense therapy that targets a glycine transporter restored NMDA receptor function in mouse models related to autism and ...

Drug peptides defy shape rules, activating receptors without full spiral form

When many of us think about how drugs work in the body, we may first think about how a drug gets into the body, such as a pill versus an injection. In the Gellman Group at the UW–Madison Department of ...
The Lancet

Oral ghrelin receptor agonist: a new promise for the improvement of systolic function

Heart failure remains a substantial cause of morbidity and mortality. Despite numerous therapeutic advancements over the past decade, there are populations in whom therapy is insufficient, ...
Frontiers

From Ethnomedicinal Plants to Receptors and Formulations: Mechanism Deconvolution for Mood and Anxiety Disorders

Mood and anxiety disorders represent a leading cause of disability worldwide. Current first-line pharmacological treatments, ...