MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today provides shareholders a ...

Signal transduction and gene regulation are at the heart of cell and developmental biology, driving cell fate decisions and tissue homeostasis. In cancer, ...

A new study has demonstrated that colon cancer cells may change identity to metastasize. Loss of GATA6, a transcription factor that controls which genes are turned on or off, can reprogram colorectal ...

A new study suggests low-intensity ultrasound can influence immune cell behavior in ways that may reduce chronic inflammation ...

Hypertrophic scars (HS) are abnormal outcomes of wound healing, marked by excessive extracellular matrix (ECM) deposition and ...

Emerging after initial responses, AR reflects tumor evolution, immune escape, and metabolic reprogramming. Key mechanisms may include impaired antigen presentation (β2-microglobulin, human leukocyte ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

An international car theft ring stole more than 100 vehicles from the D.C. area using technology available for purchase online, prosecutors say. Federal and local law enforcement officials announced ...

A couple decades ago, stealing a car was often a matter of finding a way in, twisting some wires together, and hoping nobody noticed. According to federal prosecutors, a recently busted auto theft ...

Fasting alters core physiologic processes — including inflammation regulation, energy metabolism, and neuronal plasticity — and these shifts can change the trajectory of chronic pain, particularly ...

Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in pancreatic cancer - and identified a promising strategy to overcome that ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...