Nature

Genomic analysis articles from across Nature Portfolio

Genomic analysis is the identification, measurement or comparison of genomic features such as DNA sequence, structural variation, gene expression, or regulatory and functional element annotation at a ...
IEEE

CoIn: Correlation Induced Clustering for Cognition of High Dimensional Bioinformatics Data

Abstract: Analysis of high dimensional biomedical data such as microarray gene expression data and mass spectrometry images, is crucial to provide better medical services including cancer subtyping, ...
GitHub

corto (Correlation Tool): an R package to generate correlation-based DPI networks.

Gene Network Inference, with DPI steps, Bootstrapping and optional CNV correction Gene Network Interrogation, via Master Regulator Analysis (MRA), with functions to visualize user-provided top ...
jmg.bmj

Homozygosity for CHEK2 p.Gly167Arg leads to a unique cancer syndrome with multiple complex chromosomal translocations in peripheral blood karyotype

Correspondence to Dr Hagit Baris Feldman, The Genetics Institute, Rambam Health Care Campus, Haifa 3109601, Israel; hb_feldman{at}rambam.health.gov.il Background Chromosomal instability, as reflected ...
Nature

Bioinformatics in the post-sequence era

The exponential growth in molecular sequence data started in the early 1980s when methods for DNA sequencing became widely available. The data were accumulated in databases such as GenBank, EMBL ...

Computer scientists develop a new AI tool that rivals AlphaFold 3 in mapping RNA

The same family of artificial intelligence that powers today's image generators is now being aimed at one of biology's ...
Frontiers

Biomarkers in cancer immunotherapy: Mechanisms, efficacy prediction, and irAE management

Cancer immunotherapy has transformed the landscape of oncology by mobilizing the host immune system to recognize and eradicate malignant cells. Therapeutic ...
IEEE

Statistical Analysis of Microarray Data Clustering using NMF, Spectral Clustering, Kmeans, and GMM

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...
C&EN

Novel Autoimmune Hepatitis-Specific Autoantigens Identified Using Protein Microarray Technology

Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101318, China, Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of ...
C&EN

Affinity Classification of Kinase Inhibitors by Mass Spectrometric Methods and Validation Using Standard IC

‡Novartis Institutes for Biomedical Research, Cambridge. §Novartis Institutes for Biomedical Research, Basel. Article Views are the COUNTER-compliant sum of full text article downloads since November ...
PNAS

Karrikins enhance light responses during germination and seedling development in Arabidopsis thaliana

Microarray analysis of imbibed Arabidopsis thaliana seeds was performed to identify transcriptional responses to KAR 1 before germination. A small set of genes that are regulated by KAR 1, even when ...