This joint-specific response pattern was consistent across all advanced treatment modalities, including abatacept, interleukin-6 receptor inhibitors, Janus kinase inhibitors, rituximab and TNFi.

Introduction Depression is a major global health challenge, with onset commonly occurring in youth. There is an urgent need to better understand the epidemiology of depression to facilitate better ...

Background Translating universal health coverage (UHC) commitments into explicit, evidence-informed benefits packages remains ...

Introduction Atopic dermatitis/eczema affects around 20% of children and is characterised by inflamed, dry, itchy skin. Guidelines recommend ‘leave-on’ emollients that are applied directly to the skin ...

Bhattacharya attacked study's test-negative design, a staple of vaccine effectiveness rese ...

Background Double sequential defibrillation (DSD) is a promising treatment for patients with out-of-hospital cardiac arrest ...

NT-proBNP is one of the most widely used tested biomarkers in medicine. Doctors rely on it to diagnose and monitor heart ...

The unprecedented expansion of approved oncology therapies has prolonged survival and transformed the prognosis for many patients diagnosed with cancer. However, cancer treatments may be associated ...

Oral Rotavirus vaccines have reduced disease globally but multiple factors in low- and middle-income countries (LMICs) diminish vaccine effectiveness and disease burden remains high. A convening of ...

Introduction By 2050, two-thirds of people with dementia will live in low-and-middle-income countries (LMICs). However, multimodal prevention lifestyle interventions for people at risk are being ...

The SUBITO trial, presented by Rianne L Seefat and colleagues in The Lancet Oncology,1 revisits the long-standing debate surrounding high-dose chemotherapy with autologous stem-cell rescue in patients ...

Plasma 6.7 will be the last release supporting X11; KDE moves fully to Wayland. Over 95% of Plasma 6.6 users are on Wayland; X11 usage is dwindling. XWayland and Plasma Login preserve legacy apps ...