Introductory text for Kalman and Bayesian filters. All code is written in Python, and the book itself is written using Jupyter Notebook so that you can run and modify the code in your browser. What ...

This tutorial is about the --h2-cts flag, which makes it easy to do cell type specific analyses of the sort done in Finucane et al. 2018 Nat Genet. In this example, we will replicate a piece of Figure ...

We present single-cell combinatorial indexed Hi-C (sciHi-C), a method that applies combinatorial cellular indexing to chromosome conformation capture. In this proof of concept, we generate and ...

Computational biologists have been developing standards and formats for nearly two decades, with the aim of easing the description and exchange of experimental data, mathematical models, simulation ...

Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells in which ...