A hyperspectral imaging system consists of optical, dispersive, and detection components to meet specific spatial and spectral requirements. It includes an objective lens for spatial resolution, an ...

This important study introduces a new class of spectrally tunable, dye-based calcium sensors optimized for imaging in organelles with high calcium concentrations, such as the endoplasmic reticulum and ...

Cellular imaging of the human anterior eye is critical for understanding complex ophthalmic diseases, yet current techniques are constrained by a limited field of view or insufficient contrast. Here, ...

This important study reveals that Excitatory Amino Acid Transporters play a role in chromatic information processing in the retina. The combination of (double) mutants, behavioral assays, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The recent emergence of self-driving laboratories (SDL) and material acceleration ...

I assembled the main body of the microscope using individually-purchased LEGO bricks. Instead of using motors and gears from LEGO Technic, I designed custom actuators using FreeCAD software and ...

Modern data analysis methods, such as optimization algorithms or deep learning have been successfully applied to a number of biotechnological and medical questions. For these methods to be efficient, ...

We have designed and implemented a compact, cost-efficient miniaturised light-sheet microscopy system based on optical microelectromechanical systems scanners and tunable lenses. The system occupies a ...

German scientists have built a high resolution microscope out of Lego parts and components salvaged from a mobile phone, according to a recent paper published in The Biophysicist. They found that ...

Aquatic organisms face lethal temperatures during the increasingly frequent heat waves. Knowledge of what limits survival in extreme temperatures is thus critical to predict how organisms will respond ...

The ability to simultaneously image the spatiotemporal activity signatures from many neurons during unrestrained vertebrate behaviors has become possible through the development of miniaturized ...

In an effort to help lower the costs of fluorescence microscopy and expand the use of this valuable technique in the classroom, teaching lab, and hopefully beyond, we provide two different open source ...