Genome editing lets scientists rewrite DNA, the instruction manual inside every living cell, with a precision that was unthinkable a generation ago. Technologies such as CRISPR have made this almost ...
Organoids are routinely imaged by brightfield microscopy at low magnification, but these images are challenging to analyze quantitatively at scale. Given differences in organoid-culture format and ...
Brain tumor detection is essential for early diagnosis and successful treatment, both of which can significantly enhance patient outcomes. To evaluate brain MRI scans and categorize them into four ...
We developed a system utilizing rabies virus–based monosynaptic tracing to visualize neurons that synapse onto human gliomas implanted in the mouse brain. This approach maps and quantitatively ...
1Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom. 2Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom. Search for other ...
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama ...
The process of sprouting angiogenesis can be measured in vitro using endothelial cells in sprouting assays such as the fibrin bead assay and the spheroid-based assay. While the technical aspects of ...
The primary therapeutic approach for high-grade brain tumor is surgical resection. However, identifying tumor margins in vivo remains a major challenge. Biopsy analysis remains the standard diagnostic ...
Delivering medical agents (e.g., using nanoparticles) into tumors is necessary for treating cancer. Conventional electron microscopy (EM) can visualize single nanoparticles but is limited to thin ...
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