Computing the minimal volume oriented bounding box for a given point cloud in 3D is a hard problem in computer science. Exact algorithms are known and of cubic order in the number of points in 3D. A ...
Current biophysical models poorly describe the behaviors and energetics of proteins within lipid bilayers, limiting our abilities to understand disease-related misfolding or modulate mechanisms for ...
Non-linear regression modeling is common in epidemiology for prediction purposes or estimating relationships between predictor and response variables. Restricted cubic spline (RCS) regression is one ...
Solving partial differential equations is computationally expensive, creating challenges for real-time physics simulations involving the wave equation in virtual acoustics—e.g., mixed reality, spatial ...
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Drug discovery is a challenging process with a huge molecular space to be explored and numerous pharmacological properties to be appropriately considered. Among various drug design protocols, fragment ...
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