Self-assembly of protein subunits into macromolecular complexes is ubiquitous and essential for living systems. A common obstacle during self-assembly is the formation of kinetically trapped ...
In the 1950s, four decades before he won a Nobel Prize for his contributions to game theory and his story inspired the book and film “A Beautiful Mind,” the mathematician John Nash proved one of the ...
The immune system provides the host organism with defense mechanisms against invading pathogens and tumor development and it plays an active role in tissue and organ regeneration. Deviations from the ...
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Studies on monocyte and macrophage biology and differentiation have revealed the pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue integrity by ...
We developed a theoretical framework to prove the existence and quantify the Waddington landscape as well as chreode-biological paths for development and differentiation. The cells can have states ...