More than 20% of the workload on the world's 500 fastest supercomputers is spent simulating how atoms and molecules move—with applications ranging from material design to identifying drug interactions ...

Mechanistic cardiac simulations are increasingly used in research, pharmaceutical development, and regulatory science, yet most existing human cardiomyocyte models lack the generality required for ...

GillespieSSA2 is a fast, scalable, and versatile framework for simulating large systems with Gillespie’s Stochastic Simulation Algorithm (SSA) (Cannoodt et al. 2021). This package is the spiritual ...

Happy Halloween, Rotoballers! Tonight we have an eight-game slate to kick off the Emirates NBA Cup in-season tournament. Last season, teams used slightly condensed rotations and leaned on their stars ...

The ABM package provides a high-performance, flexible framework for agent-based modeling. It has an easy-to-use state transition mechanism, that makes it especially suitable for modeling agent based ...

The Gillespie algorithm provides statistically exact methods for simulating stochastic dynamics modeled as interacting sequences of discrete events including systems of biochemical reactions or ...

This important study introduces a fully differentiable variant of the Gillespie algorithm as an approximate stochastic simulation scheme for complex chemical reaction networks, allowing kinetic ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

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