A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...
Cells can adapt to various environments by changing their biomolecular profiles while maintaining physiological homeostasis. What organizational principles in cells enable the simultaneous realization ...
Centrality measures allow to identify important nodes in networked systems. An open question in network theory is the empirical observation that a node’s centrality—whose computation requires ...
The stock market is a canonical example of a complex system, in which a large number of interacting agents lead to joint evolution of stock returns and the collective market behavior exhibits emergent ...
Our main message is that the popular method of low-dimensional embeddings provably cannot capture important properties of real-world complex networks. A widely used algorithmic technique for modeling ...
In chemistry, the properties of atoms and molecules can be determined by solving the Schrödinger equation. However, because the dimension of the problem grows exponentially with the size of the ...
There is growing evidence that much more of the genome than previously thought is required to explain the heritability of complex phenotypes. Recent studies have demonstrated that numerous common ...
A question that arises often when discussing the optimal role of science in medicine is the precise role of plausibility, or prior probability. This is, in fact, the central concept that separates ...
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