MedPage Today

JAMA Journal Publishes COVID Vaccine Study Squelched by CDC Leader

A study on COVID vaccine effectiveness that was suppressed by the CDC's acting director, due to its test-negative design, has ...
qualitysafety.bmj

Investigating a novel population health management system to increase access to healthcare for children: a nested cross-sectional study within a cluster randomised controlled trial

Background Early intervention for unmet needs is essential to improve health. Clear inequalities in healthcare use and outcomes exist. The Children and Young People’s Health Partnership (CYPHP) model ...
The Lancet

Plasma metabolomic profiles and risk of hip fracture among US individuals: a nested case–control and prospective cohort study

aDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA bDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA cChanning Division of ...
GitHub

Context Cascade - Nested Plugin Architecture for Claude Code

Traditional approach: Load everything upfront = 100k+ tokens consumed Context Cascade: Load on demand = ~2k tokens initially, expand as needed Result: 90%+ context savings while maintaining full ...
Frontiers

Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive ...

Major depressive disorder (MDD) frequently results in suboptimal treatment outcomes and elevated recurrence rate, with patients frequently engaging in self-harm and suicidal behavior, thereby placing ...
BMJ

Combining high quality data with rigorous methods: emulation of a target trial using electronic health records and a nested case-control design

4 Department of Epidemiology, University of Washington, Seattle, WA, USA 5 Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA 6 ...
ahajournals.org

Effect of Smoking Cessation on the Risk of Subarachnoid Hemorrhage: A Nested Case-Control Study in Korean Men

Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea (T.O.). Department of Neurology (T.O., J.J., J.K.), Yonsei ...
The New England Journal of Medicine

Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections

The protection conferred by natural immunity, vaccination, and both against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with the BA.1 or BA.2 sublineages of the ...
BMJ

Diseases prevalent before major depressive disorder diagnosis: an exploratory nested case–control study using health insurance-based claims data

Objectives Major depressive disorder (MDD) is often comorbid with other chronic and/or serious diseases. However, little is known about the prevalence of various diseases that are present before MDD ...
BMJ

Epilepsy and mortality: a retrospective cohort analysis with a nested case–control study identifying causes and risk factors from primary care and linkage-derived data

3 NIHR Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London, London, UK Objectives People with epilepsy (PWE) have a higher mortality rate than the general ...
thorax.bmj

Risk of drug-induced interstitial lung disease in hospitalised patients: a nested case–control study

Correspondence to Dr Taisuke Jo, Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; jo-taisuke{at}umin.ac.jp Introduction Information on ...