Frontiers

Bruceine E, a natural quassinoid from Brucea javanica, inhibits PARthanatos via targeting PARP1 in ischemic stroke

Ischemic stroke currently lacks evidence-based neuroprotective agents, primarily due to the challenge of timely intervention, which often occurs after the onset of irreversible neuronal damage. To ...
Frontiers

EURAD state-of-the-art report on the understanding of radionuclide retention and transport in clay and crystalline rocks

After isolation of radioactive waste in deep geological formations, radionuclides can enter the biosphere via slow migration through engineered barriers and host rocks. The amount of radionuclides ...
C&EN

Newly Synthesized Pyrazolinone Chalcones as Anticancer Agents via Inhibiting the PI3K/Akt/ERK1/2 Signaling Pathway

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Article Views ...
C&EN

Recommendations and Standardization of Biomarker Quantification Using NMR-Based Metabolomics with Particular Focus on Urinary Analysis

¶ Northwest Metabolomics Research Center, Department of Anesthesiology and Pain Medicine, University of Washington, 850 Republican Street, Seattle, Washington 98109, United States + Northwest ...
Independent.ie

Sisk family give company cash injection after losses on unpaid work

The family behind building contractors Sisk Group pumped €15m into the business last year to help cope with losses of almost €100m in Poland. John Sisk & Sons suffered losses of €98m over two years ...
PNAS

Oxygen doping of cobalt-single-atom coordination enhances peroxymonosulfate activation and high-valent cobalt–oxo species formation

High-valent metal–oxo species have attracted extensive attention for water purification because of their relatively high reductive potential and long half-life, but are still limited by inefficient ...