Networks of protein fibers play important roles in living cells. To understand the dynamical behavior of these networks, model networks are needed to perform in vitro studies. However, fabrication of ...
The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...
Green fluorescent protein has an iconic structure. National Institute of General Medical Sciences/National Institutes of Health via Flickr, CC BY-NC Fruit flies, mice, zebra fish, yeast and the tiny ...
Abstract: The analysis of molecular cavities, where ligands interact with protein structures, plays a critical role in protein structure-based drug design. However, it is a challenge because of the ...
Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...
The advent of the big data era has made data visualization a crucial tool for enhancing the efficiency and insights of data analysis. This theoretical research delves into the current applications and ...
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Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The ...
Summary: Researchers have developed a system that detects genetic markers of autism in brain images with 89-95% accuracy, potentially enabling earlier diagnosis and treatment. This method, which ...
Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and ...
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