A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...
Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect ...
The transition of healthy arteries and cardiac valves into dense, cell-rich, calcified, and fibrotic tissues is driven by a complex interplay of both cellular and molecular mechanisms. Specific cell ...
Technological advances in characterizing molecular heterogeneity at the single cell level have ushered in a deeper understanding of the biological diversity of cells present in tissues including ...
An educational tutorial and working demonstration pipeline for RNA-seq analysis including an introduction to: cloud computing, next generation sequence file formats, reference genomes, gene annotation ...
Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...
In the years after the 2020 COVID-19 pandemic, it is clear that mRNA as a modality for vaccines and therapeutics is here to stay based on the number of mRNA programs currently in clinical development.
At AACR 2024, we explored the poster hall to pick out the posters that would interest the BioTechniques reader and those we found delivered the most interesting or surprising findings. Get our ...
Fluid shear stress mediates vascular homeostasis by regulating gene expression in endothelial cells (ECs). Using single-cell RNA sequencing, this study provides a comprehensive perspective of ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results