Atomic 'domino effect' found to drive phase changes in a two-dimensional crystal

Phase transformations—in which a material changes from one crystal structure to another, thereby acquiring dramatically ...
The Lancet

Fecal microbiota transplantation plus tislelizumab and fruquintinib in refractory microsatellite stable metastatic colorectal cancer: an open-label, single-arm, phase II trial ...

aDepartment of Clinical Oncology, Renmin Hospital of Wuhan University, Wuhan, China bDepartment of Clinical Oncology, Qianjiang Central Hospital, Qianjiang, China cDepartment of Abdominal Tumor ...
The Lancet

First-line systemic treatment strategies in patients with initially unresectable colorectal cancer liver metastases (CAIRO5): an open-label, multicentre, randomised, controlled ...

aDepartment of Epidemiology, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands bDepartment of Surgery, University Medical ...
Frontiers

Methods to improve the accuracy of next-generation sequencing

Next-generation sequencing (NGS) is present in all fields of life science, which has greatly promoted the development of basic research while being gradually applied in clinical diagnosis. However, ...
Frontiers

Methanogen Community Dynamics and Methanogenic Function Response to Solid Waste Decomposition

The world is facing the challenges of energy shortage and climate change. Various innovation techniques are developing to produce and recover clean energy such as methane (Niu et al., 2014; Li et al., ...
Front Line Genomics

The evolution of DNA sequencing technologies

The order of nucleotides within a sequence of DNA is important. It underpins subsequent protein function and, in cases of mutations, the subsequent disease manifestation. Determining the order of ...
C&EN

DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis

The promise of exploiting combinatorial synthesis for small molecule discovery remains unfulfilled due primarily to the “structure elucidation problem”: the back-end mass spectrometric analysis that ...
C&EN

Pyrosequencing Reveals the Key Microorganisms Involved in Sludge Alkaline Fermentation for Efficient Short-Chain Fatty Acids Production

This file contains Table S1 and Figures S1–S3. This material is available free of charge via the Internet at http://pubs.acs.org. Smart citations by scite.ai ...
Cancer Research

A Phase I Trial of Liposomal Doxorubicin, Bevacizumab, and Temsirolimus in Patients with Advanced Gynecologic and Breast Malignancies

Clin Cancer Res (2011) 17 (21): 6840–6846. Purpose: Liposomal doxorubicin (D) and bevacizumab (A) are active single agents in gynecologic and breast malignancies which share a resistance mechanism: ...
Europe PMC

Horizon-specific bacterial community composition of German grassland soils, as revealed by pyrosequencing-based analysis of 16S rRNA genes.

The diversity of bacteria in soil is enormous, and soil bacterial communities can vary greatly in structure. Here, we employed a pyrosequencing-based analysis of the V2-V3 16S rRNA gene region to ...
Europe PMC

Accuracy and quality of massively parallel DNA pyrosequencing.

Massively parallel pyrosequencing systems have increased the efficiency of DNA sequencing, although the published per-base accuracy of a Roche GS20 is only 96%. In genome projects, highly redundant ...