Human C-reactive protein (CRP) activates the complement system to protect us from infections, but can also contribute toward progression of cardiovascular and autoimmune diseases when misactivated.

Many tools exist to improve antibody effector function in vitro. While these protein engineering approaches have improved efficacy in mouse models, proof of improved activity in primates has been ...

Pemphigoid diseases are autoimmune chronic inflammatory skin diseases, which are characterized by blistering of the skin and/or mucous membranes, and circulating and tissue-bound autoantibodies. The ...