Tumor relapse remains a significant obstacle to successful therapy. Preclinical animal models that accurately reflect tumor relapse in patients are urgently needed. Here, we employed a dual ...

This important study dissects the mathematical and biological assumptions underlying the commonly used Activity-by-Contact model of enhancer action in transcriptional regulation. The authors provide a ...

The atmosphere and seawater are facing an increase in carbon dioxide (CO 2) concentrations. Global carbon analyses have reported that atmospheric CO 2 levels increase from 280 parts per million (ppm) ...

Burkina Faso rewards wildlife travelers with classic West African savanna safaris-especially in the transboundary W-Arly-Pendjari complex-where elephants, antelopes, primates, and standout birdlife ...

Understanding how genomic regulatory elements interact to control spatiotemporal gene expression is essential to explaining cell type diversification, function, and delineating genetic variation and ...